Leg pain can have a ton of causes ranging from so very benign to life threatening–and one of those possible causes is irritable bowel syndrome.

Having pain in your leg and wondering if this is related to your irritable bowel syndrome?

Your one burning question is: “Can IBS cause leg pain?”

“Yes! The underpinnings of IBS are fascinating, and this underpinning helps explain the leg pain,” says Pejman Katiraei, DO, FAAP, an integrative physician whose many areas of specialty include adult and pediatric IBS.

“To start, we must recognize that people with IBS have inflammation in their intestines. Inflammation means that there is increased immune activity in a part of the body.”

An example of this would be the redness that occurs around a cut in your skin, or the swelling of a sprained ankle.

“People with IBS have inflammation in their intestines,” continues Dr. Katiraei.

“This inflammation typically involves a specific type of immune cell called mast cells.”

A doctor may give an endoscopy to a person with IBS, but tell that patient that all is normal … because pathologists are not able to see the mast cells via standard biopsy analysis.

The problem is there, says Dr. Katiraei, but it goes unseen. This is why people with IBS are often told that nothing is wrong.

But Dr. Katiraei continues, “If doctors used very sensitive tools like electron microscopes or very specialized immune stains, they will find these changes in the intestines.

“In the bowel, sitting right next to these mast cells are nerve cells that take information from the intestines to the spinal cord.”

During an inflammatory process, the mast cells release chemicals that can irritate nerve cells.

“The irritated nerve cells then send signals to the spinal cord that there is something very wrong,” says Dr. Katiraei.

“Our brain interprets this signal as pain. It so happens that the nerves from the legs merge in the spinal cord in the same area as the intestines. The signal from the gut and the legs gets mixed up.”

This is called viscerosomatic convergence and it tricks the brain.

“The pain signal from the intestines gets mixed up as a pain signal from the legs.”

So indeed, a person with IBS can definitely experience a perception of pain in the legs. The leg pain here is actually from the intestines.

Dr. Katiraei adds, “When the inflammation in the intestines calms down, so does the inflammation in the joints, and the pain disappears.”

Dr. Katiraei created Wholistic Kids and Families for people interested in learning how to raise a healthy child (and future adult) in a world that’s becoming increasingly polluted with toxins (chemical and emotional).
Lorra Garrick has been covering medical, fitness and cybersecurity topics for many years, having written thousands of articles for print magazines and websites, including as a ghostwriter. She’s also a former ACE-certified personal trainer.  

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