Why Is the Prognosis for Nail Melanoma Much Worse than Skin?

Yes, melanoma can grow in the nail unit, and it’s a well-known fact among dermatologists that this type of melanoma has a poor prognosis. “Nail melanoma, which is in the category of acral lentiginous melanoma [...]

How Ugly Can a Tiny Melanoma Look?

Tiny melanoma, 1.6 mm. Source: Dermatol Pract Concept. 2013 Apr. Copyright ©2013 Pellizzari et al. Articles and pamphlets refer to melanoma as the “ugly duckling” or “ugly mole.” But how “ugly” or “different” [...]

6 Year Old’s Nail Mole Likely Melanoma or just a Birth Mark?

A mother of a six year old wanted to know if an elongated mole in her child’s nail could possibly be melanoma. How likely would this just be a harmless mark of pigmentation from birth? [...]

Severely Atypical Mole with Regression: Time to Worry

If you have a severely atypical, irregular or dysplastic mole that’s showing signs of regression (new areas of milky-white color), this is very worrisome for melanoma. A white “spot” in a mole isn’t always cancerous, [...]

Longitudinal Melanonychia vs. Subungual Melanoma

Subungual melanoma is a type of longitudinal melanonychia, but what are the tipoffs that longitudinal melanonychia is malignant vs. benign? A brown or black band, stripe, streak or line in a nail is a very [...]

What Is a Micro-Hutchinson’s Sign?

Blue arrows point to Hutchinson’s sign from melanoma shown under magnification. Copyright ©2018 Bhat et al If you know what a Hutchinson’s sign is, perhaps you’re wondering just what is a micro-Hutchinson’s sign [...]

Nodular Melanoma: What You Should Know About this Killer

Nodular melanoma is a particularly lethal form of cancer that disregards the ABCDE guidelines that are so publicized about melanoma. Delayed diagnosis is more common with nodular melanoma than with the more common superficial spreading [...]

Is a Mole Normal if It’s Brown and Grey or Can It Be Melanoma?

A normal mole is supposed to be one color, or at least, two shades of a color. But brown and grey are two completely different colors. Is this melanoma? […]

How Fast Actinic Keratosis Turns into Squamous Cell Carcinoma?

Actinic keratosis Though most squamous cell carcinomas were once actinic keratoses, most AK’s will not turn into cancer. However, it’s impossible to predict which lesions will eventually begin undergoing a malignant transformation. [...]

Do ALL Nail Melanomas Have a Hutchinson’s Sign?

The Hutchinson’s sign is a very tell-tale sign of fingernail or toenail melanoma. Further complicating this issue is that benign pigment in a nail can mimic a true Hutchinson’s sign. […]

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