There are several possible causes of red itchy bumps on your palm, and one of these causes is especially serious, says Gary Goldenberg, MD, a dermatologist.

He runs Goldenberg Dermatology, and is assistant professor of dermatology and pathology at Mount Sinai School of Medicine.

“Most commonly, especially in adults, this is a manifestation of hand dermatitis, a type of eczema,” says Dr. Goldenberg.

“Allergic contact dermatitis may cause this alone or in combination with eczema.

“Psoriasis can also cause itchy bumps on the hands. Fungal infection of the hands usually presents with scaly patches, but can cause bumps as well. Syphilis can also look like this.”

Syphilis is the serious disorder here. And why is this sexually transmitted disease so serious?

The first symptom is a painless sore usually on the genitals or in the mouth.

The sore will go away but this does not mean you’re out of the woods.

Though the disease can be often cured with just one penicillin injection, it can also kill if left untreated.

After the initial sore heals, a rash may develop and cover the entire body, including the palms. It may not itch, but it also may.

There can be other symptoms too such as hair loss, sore throat and wart-like sores in the mouth.

In people who never get treated for syphilis, about 15 to 30 percent develop the “tertiary” form of the disease.

At this point the infection can damage the brain, eyes, nerves, blood vessels, liver and bones.

These complications may start up many years after the original and untreated infection.

Solutions for Itchy Red Bumps on the Palm

“Treatments vary between steroid creams for psoriasis, eczema or allergic contact dermatitis.

“A blood test is usually needed to diagnose syphilis, and antibiotics are needed for treatment.”

And remember, the fact that a course of antibiotics can resolve syphilis does not mean that this sexually transmitted disease is nothing to worry about.

Dr. Goldenberg of Goldenberg Dermatology provides comprehensive care in medical and cosmetic dermatology, including melanoma and other skin cancer, moles, psoriasis, eczema and acne. He is the medical director of the Dermatology Faculty Practice, NY.
Lorra Garrick has been covering medical, fitness and cybersecurity topics for many years, having written thousands of articles for print magazines and websites, including as a ghostwriter. She’s also a former ACE-certified personal trainer.  

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