Even if your CIN 1 has turned to CIN 2, you’re still not near the cancer danger zone sitting at CIN 2.

This is because if we skip a step in the progression, meaning, look at the progression of CIN 3 to cervical cancer, we’re still looking at quite a bit of time.


When women learns that her Pap smear shows CIN 1 (low grade cervical intraepithelial neoplasia), this is alarming news to many once they know that CIN 1 is the first stage of a transformation process that has the potential to culminate in cervical cancer.

Some women will opt for the wait-and-see approach when they’re diagnosed with CIN 1, since surgical removal of the abnormal tissue isn’t exactly a picnic.

In fact, the standard recommendation is simply a follow-up Pap smear several months later.

It’s during that wait-and-see period that they fear that CIN 1 will turn into cancer, even though the follow-up Pap may be scheduled for only six months out.

“Most CIN 1 and 2 will resolve spontaneously (75%),” says Julian Schink, MD, Chief of Gynecologic Oncology, Cancer Treatment Centers of America; Medical Director of Gynecologic and Medical Oncology, Midwestern Regional Medical Center.

Dr. Schink adds, “Some will progress to CIN 3 or cancer, but it takes many years. The median age of CIN 3 is 34 yo, and the median age of cervical cancer is 44 yo, suggesting that on average it takes 10 years for that last step (with a range of 4-20).”

If you’re still petrified over being diagnosed with CIN 2 or even CIN 1 and don’t think you can tolerate a wait-and-see approach for a follow-up Pap smear, you should discuss treatment options with your gynecologist.

For more information on cervical cancer screening or treatment, contact Cancer Treatment Centers of America at (844) 632-7188. cin 1, 2
dr. schinkWith 25+ years of experience, and board certified in gynecologic oncology and OB/GYN, Dr. Schink is dedicated to caring for patients and advancing treatments for gynecologic malignancies. His surgery and chemotherapy treatments include those for ovarian, cervical and uterine cancer. 



Top image: Shutterstock/ANN PATCHANAN