There are different kinds of gallbladder polyps and this includes cancer.
So if it’s been discovered that you have a polyp in your gallbladder, should you panic and assume that it’s cancer?
Will the mass eventually transform into a malignancy?
There are no grounds for panicking or making this assumption, as there are several types of polyps associated with this organ.
A Polyp Was just Discovered in Your Gallbladder
“Gallbladder polyps are outgrowths of the gallbladder mucosal wall that are usually found incidentally on ultrasonography or after cholecystectomy,” says Akram Alashari, MD, abdominal surgeon and critical care physician, Department of Surgery, College of Medicine, University of Florida.
Two Classes of Gallbladder Polyps
“They are classified as benign or malignant, and benign lesions are further classified as non-neoplastic (e.g., cholesterol and inflammatory polyps, adenomyomas) or neoplastic (e.g., adenomas, leiomyomas),” says Dr. Alashari.
Don’t be unnerved by the “oma” suffix here. “Oma” is the medical term for mass—but the mass can be benign.
“The most common benign neoplastic lesion is an adenoma, a glandular tumor composed of cells resembling biliary tract epithelium.
“It is unclear whether adenomatous polyps represent a premalignant lesion and if so, the frequency with which they progress to carcinoma.”
Cancer-related molecular changes that are seen in gallbladder cancers have not been identified in adenomas.
“Nevertheless, larger polyps are more likely to contain foci of invasive cancer, and some studies suggest a correlation between the presence of gallbladder polyps and the risk of gallbladder cancer.”
Symptoms of Gallbladder Cancer
- Abdominal pain, especially in the upper right region
- Abdominal bloating
- Weight loss that is not intentional or explainable
- Yellowing of the whites of the eyes or the skin (jaundice)
Risk factors for this disease include aging, female gender and a history of gallstones.
However, the disease is still rare in people who’ve had gallstones.
Another risk factor is infection of this organ.
Gallbladder cancer is a rare condition. The occurrence in the U.S. is 12.3 per 100,000 men and 27.3 per 100,000 women.