So, your toe is twitching.

Maybe it’s the big one only, or maybe it’s a few of the smaller ones, but nevertheless, the twitching is hard to ignore.

Especially when you can actually see the toes jump under your socks.

When a toe twitches, it’s because of an electrical misfire in the motor neuron unit in the muscle, but this isn’t the cause per se; it’s only the mechanism.

Toe twitching is perfectly normal, but can have a variety of causes.

Sometimes, toe twitching can be caused by scrunching up the digits, which you may not be aware you’re doing.

This actually causes twitching in the tiny muscles in some cases.

Because these muscles are so small, and the toe itself is such a small fixture of the body, it shouldn’t be any surprise that when it twitches, you can see it “jump.”

If two toes twitch in unison, this is nothing at all to be worried about.

For example, the third and fourth ones may twitch together, in synch.

But this is perhaps due to the fact that in anything, these particular toes usually act in unison.

Try lifting the fourth one without the third one coming up, for instance.

Twitching in these tiny muscles is completely normal and there is very little reason to fear you might have a disorder like ALS or MS.

The Key Point

“The key point with benign fasciculations is that, for whatever reason, they occur but do not represent an ominous underlying condition,” affirms Kristina Lafaye, MD, a board certified neurologist. 

“Yes, some people with benign fasciculations could experience them 24/7 (or so they say; I’m a little skeptical of that), but if nothing else is wrong, then I wouldn’t probe further,” adds Dr. Lafaye, full time clinical staff and director of the neurophysiology lab at Ochsner Medical Center.

“I don’t do any kind of a frequency count, because if a person doesn’t have evidence of denervation which, if present, would indicate a MND, myelopathy, or some other condition, then it doesn’t warrant any further neurologic evaluation.”

Causes of Toe Twitching

Tensing up the toes (anxiety, habit)

Improper footwear, especially a tight toe box


Pressure on a nerve (shoes, foot position while seated or lying down)

Anxiety (not necessarily about what’s causing your toes to twitch, but anything that can cause apprehension)

Insufficient calcium and magnesium intake





Only in very rare cases is muscle twitching caused by a disease.

Perhaps while you were on the verge of falling asleep, your toe twitched.

This isn’t the same kind of twitching that happens when you are wide awake.

This type of “twitch” is actually called a myoclonus: an involuntary jerking of a muscle.

Myoclonus jerks as you drift to sleep occur in healthy people and rarely mean a problem.

More severe myoclonus may be brought on by medication or head trauma.

However, there is also a paranormal explanation for the causes of this kind of twitching, regardless of which muscles it occurs in; myoclonus occurs in different muscles.

The paranormal explanation is that your astral double has left your body (out of body experience) without you knowing this, and when it’s time to return, it re-enters rather abruptly, and you feel this as the myoclonus!

Dr. Lafaye is assistant professor of clinical neurology, and director, Neurology Student Education at Tulane University School of Medicine.
Lorra Garrick has been covering medical, fitness and cybersecurity topics for many years, having written thousands of articles for print magazines and websites, including as a ghostwriter. She’s also a former ACE-certified personal trainer.  
Top image: Shutterstock/Alexander Raths

Can Twitching in the Butt Mean Serious Medical Condition?

Thigh Muscle Twitching: Don’t Worry, or Panic?

Why Does My Eyelid Twitch After I Sneeze?

Muscle Twitching in Fingers? ALS Fear? Strength Tests

Why Muscles Seem to Twitch More When at Rest