barrett's esophagus progression

If you’ve been suffering a long time from acid reflux, you may want to ask your doctor about a barium swallow test to screen for Barrett’s esophagus, a precancerous condition.

The damage that the acidic contents from the stomach causes to the inner lining of the esophagus can lead to cellular changes: a change in cells that create a risk factor for esophageal cancer.

A barium swallow is designed to detect this precancerous condition.

But if someone has had severe acid reflux over a long course of time, is it ever possible for the barium swallow to come up negative?

“A barium swallow can absolutely be normal despite severe reflux, because a barium swallow is made to show changes in anatomy in the esophagus and stomach,” says Alan Gingold, DO, a board certified gastroenterologist with the Digestive Health Center of NJ.

“It will show masses or ulcers, but if there is no significant damage from the reflux, the barium swallow may appear normal.”

Barrett’s Esophagus

About two percent of people with Barrett’s esophagus eventually develop esophageal cancer, which has a dismal five year survival rate of a little over 19 percent, according to the National Cancer Institute Surveillance and Epidemiology End Results Program.

You may be wondering if, in the event your barium swallow turns up normal, you should just have one done every year to catch Barrett’s esophagus at its earliest.

However, this is not what people with gastroesophageal reflux disease should do.

Dr. Gingold explains, “Unfortunately, because Barrett’s esophagus is a pathological diagnosis — meaning that it is based on biopsy results, it cannot be followed by barium swallow studies. The only way to follow Barrett’s esophagus in patients with reflux is to do an EGD (esophagogastroduodenoscopy) every three to five years.