Can DVT pain in the calve, and the pain of a pulled muscle in the calve, be distinguished? DVT stands for deep vein thrombosis: a blood clot. 

A blood clot in the calve can cause aching or discomfort. So can a pulled or strained muscle in this region.

If there a way to tell the difference between blood clot pain and that which results from a sore or pulled muscle in the calve?

“It is going to be difficult,” says Dr. Moji Gashti, Chief, Division of Vascular Surgery, Department of Surgery, Union Memorial Hospital, Baltimore, MD.

“Both most likely would present with achy kind of pain,” continues Dr. Moji.

“Perhaps the history may be more important here; a pulled muscle most likely would happen with some kind of trauma or activity as opposed to pain related to deep vein thrombosis, which most likely would happen in an individual after some inactivity (post-op, cast, long trips, etc.).

“The pain from DVT most likely would also come about slowly rather than suddenly, and be associated with swelling.”

As you can see, a better way to tell the difference between a DVT and a pulled muscle is by evaluating the preceding activity—or lack thereof. Nevertheless, if you suspect a blood clot, head immediately to the emergency room. An ultrasound can make the proper diagnosis.